The Effect of an antioxidant agent-multivitamin complex food supplement on spermiogram in infertile men
DOI:
https://doi.org/10.46328/aejog.v5i2.137Keywords:
male infertility , astaxhantin, oxidative stress, spermiogramAbstract
giriiş
Oxidative stress (OS) occurs due to overproduction of reactive oxygen radicals (ROS) or weakening of anti-oxidant mechanisms and may harm fertility. Our study aimed to investigate the effects of combined support therapy containing antioxidant agents and vitamin complexes on fertility.
Material method
In this retrospective case-control study, 300 randomly selected infertile men were included. For four months, the effect of daily intake of an antioxidant-multivitamin complex containing astaxhantin (5mg), Coenzyme Q10 (100mg), L-Arginine (250mg), L-Carnitine (250mg), Selenium (100mcg), Zinc (10mg), Folic acid (400mcg), Vitamin E (100mg) and Vitamin C (100mg) on spermiogram parameters was investigated.
Results
Semen hacminde (2.21 ml -3.05 ml; p=.004), sperm konsantrasyonunda (9.60 milyon/ml -14.10 milyon/ml; p=.000), ileri hareketli sperm sayısında (%16.50 -%26.65; p=.000) ), sperm canlılık oranında (%48 - %68; p=.001) beslenme desteği alan hastalarda istatistiksel olarak anlamlı artış bulundu. Ayrıca tedavinin anormal morfolojiye sahip hasta sayısında (Kruger kriterlerine göre normal morfolojiye ulaşamayan hastaların en az %4'ü) anlamlı azalma (%77 - %61; p=.002) sağladığı belirlendi. ).
Çözüm
Astaxhantin, KoQ10, L-arjinin, L-karnitin, selenyum, çinko, E ve C vitaminleri içeren antioksidan-multivitamin içerikli besin takviyelerinin semen hacmi, sperm morfolojisi, canlılık ve motilite üzerinde anlamlı iyileşme sağladığı belirlendi. Bu bağlamda antioksidan-multivitamin kompleksinin erkek kısırlığında destekleyici tedavi için gıda takviyesi olarak kullanılabileceğini öngörüyoruz.
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